Marco Milanese
University of Genoa, Italy
Biography
Marco Milanese is Associate Professor at the Department of Pharmacy of the University of Genoa. Since 2005 Marco Milanese is member of the Pharmacology and Toxicology research Unit of the Department of Pharmacy, University of Genoa, working in the field of neuropharmacology and neurosciences. Marco Milanese holds a long-lasting experience in training undergraduate students and PhD students other than managing a biological research laboratory with a broad panel of expertise and facilities. The scientific research of Marco Milanese started focusing on various aspects of neurotransmission and relative molecular mechanisms underlying neurological disorders and neurodegenerative diseases: release of neuro- and glio-transmitters and modulation systems, pre-synaptic proteins, pharmacological characterizations of pre- and postsynaptic glutamatergic receptors. In this context the research activity of M. Milanese was mainly focused on the study of glutamatergic neurotransmission linked to excitotoxicity in neurodegenerative diseases with particular interest on motor neuron diseases (MND) and amyotrophic lateral sclerosis (ALS). In the last ten years the research activities of M. Milanese were characterized by in-vivo behavioural analysis and ex-vivo histological studies to assess the clinical progression and the molecular dysfunction in mouse model of ALS and/or other neurological disorders. The areas of investigation, in the context of ALS, have then expanded towards complementary in-vitro functional and biochemical studies on motoneuron, astrocyte, microglia and oligodendrocyte primary cell cultures acutely isolated from ALS mouse models. M. Milanese holds active scientific collaborations with National and International research groups, as intelligible from the publication track record.