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Graciela Mahler

University of the Republic, Uruguay

Biography

Graciela Mahler, PhD, Professor of Organic Chemistry was born in Paysandú Uruguay. She Started out in education for Chemistry for some years. Bachelor of Science, Chemistry – 1992, Universidad de la República (UdelaR), Montevideo, Uruguay. 2003 she got her PhD in organic chemistry, Montevideo UdelaR and in 2004 was a pos doc at the Chemistry Department, University of Pittsburgh. Since 2005 is a professor at the University of the Republic. Over the last 17 years her main scientific interest includes the development of enzyme inhibitors using different tools like: dynamic combinatorial chemistry, bioisosterism and virtual screening. She focuses on the development of new synthetic methodologies for the rapid generation or molecular complexity to evaluate it bioactivity against trypanosomatids, helmints, viruses and bacteria. Awards: Researcher level II of the National Agency of Research and Innovation (ANII) (2015 to present), Member of the PEDECIBA council (2021 to present), Thieme Chemistry Journal Award (2013).

Abstract

Abstract : Selenosemicarbazones as new inhibitors of the main proteases of SARS-CoV-2