Marco Milanese
University of Genoa, Italy
Biography
Marco Milanese is Associate Professor at the Department of Pharmacy of the University of Genoa. The scientific interest of Milanese Marco focuses on various aspects of neurotransmission and the molecular mechanisms involved in neurodegenerative processes; the research activity of Milanese Marco is characterised by the study of glutamatergic neurotransmission linked to excitotoxicity in neurodegenerative diseases, with particular interest to amyotrophic lateral sclerosis (ALS). The current research lines of Marco Milanese are aimed at studying the etiopathological mechanisms of ALS and develop translational strategies, by exploiting in-vivo behavioural analyses on experimental mouse models of ALS as well as functional in-vitro studies on motoneuron, astrocyte and microglia primary cell cultures. In this framework, very recently, Milanese Marco demonstrated the pivotal role of Group I mGluR receptors supporting the progression of ALS pathology. This research topic might pave the way for new therapeutic approach to counteract MN degeneration and ALS course.
Marco Milanese is Associate Professor at the Department of Pharmacy of the University of Genoa. The scientific interest of Milanese Marco focuses on various aspects of neurotransmission and the molecular mechanisms involved in neurodegenerative processes; the research activity of Milanese Marco is characterised by the study of glutamatergic neurotransmission linked to excitotoxicity in neurodegenerative diseases, with particular interest to amyotrophic lateral sclerosis (ALS). The current research lines of Marco Milanese are aimed at studying the etiopathological mechanisms of ALS and develop translational strategies, by exploiting in-vivo behavioural analyses on experimental mouse models of ALS as well as functional in-vitro studies on motoneuron, astrocyte and microglia primary cell cultures. In this framework, very recently, Milanese Marco demonstrated the pivotal role of Group I mGluR receptors supporting the progression of ALS pathology. This research topic might pave the way for new therapeutic approach to counteract MN degeneration and ALS course.