Poi Yee Cheong
Monash University, Malaysia
Biography
Poi Yee Cheong is currently pursuing her PhD degree at Monash University Malaysia. She has completed her Master degree in Medical Sciences at International Medical University, Malaysia. Her research interests focus on the characterization of the molecular mechanisms of benzyloxycarbonyl-phenylalanine-alanine-fluoromethylketone (z-FA-FMK) and benzyloxycarbonyl-phenylalanine-alanine-chloromethylketone (z-FA-CMK) induced toxicity in T cells. Both compounds are structurally similar; the former with fluorine in the methylketone group is immunosuppressive whereas the latter with chlorine induced cell death.
Abstract
Abstract : The cathepsin B inhibitor, z-FA-FMK inhibits jurkat T cell proliferation through oxidative stress